Transcriptomics

Dataset Information

2

Cellular and Molecular Immune Profiles in Renal Transplant Recipients after Conversion from Tacrolimus to Sirolimus


ABSTRACT: Tacrolimus and Sirolimus are commonly used to maintain immunosuppression in kidney transplantation. However, their effects on immune cells and allograft molecular profiles have not been elucidated. Here we characterized the effects of Tacrolimus to Sirolimus conversion on frequency and function of T cells, and on graft molecular profiles. Samples from 30 renal transplant recipients in a randomized trial of late Sirolimus conversion (n=18) vs. Tacrolimus maintenance (n=12) were utilized. Peripheral blood was collected at 0- 6- 12 and 24-months post-randomization. This dataset only contains the 18 arrays corresponding to patients treated with Sirolimus.

ORGANISM(S): Homo sapiens  

SUBMITTER: Valeria Mas   Catherine I Dumur  Daniel Maluf  Catherine Dumur 

PROVIDER: E-GEOD-55998 | ArrayExpress | 2014-09-17

SECONDARY ACCESSION(S): GSE55998PRJNA242138

REPOSITORIES: GEO, ArrayExpress

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