Dataset Information


Genome-wide analysis of histone modifications in human endometrial stromal cells

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens  

SUBMITTER: Isao Tamura   

PROVIDER: E-GEOD-57010 | ArrayExpress | 2015-03-07



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Genome-wide analysis of histone modifications in human endometrial stromal cells.

Tamura Isao I   Ohkawa Yasuyuki Y   Sato Tetsuya T   Suyama Mikita M   Jozaki Kosuke K   Okada Maki M   Lee Lifa L   Maekawa Ryo R   Asada Hiromi H   Sato Shun S   Yamagata Yoshiaki Y   Tamura Hiroshi H   Sugino Norihiro N  

Molecular endocrinology (Baltimore, Md.) 20140729 10

Dramatic changes of gene expressions occur in human endometrial stromal cells (ESCs) during decidualization. The changes in gene expression are associated with changes of chromatin structure, which are regulated by histone modifications. Here we investigated genome-wide changes in histone modifications associated with decidualization in human ESCs using chromatin immunoprecipitation combined with next-generation sequencing. ESCs were incubated with estradiol and medroxyprogesterone acetate for 1  ...[more]

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