Transcriptomics

Dataset Information

4

Genomic analysis of low-grade serous ovarian carcinomas [ILOEF]


ABSTRACT: Low-grade serous ovarian carcinomas are typically Ras-pathway mutated, TP53 wild-type, have limited chromosomal aberration, and are frequently associated with borderline tumors. By contrast, high-grade serous ovarian carcinoma lack Ras-pathway mutations, are invariably TP53 mutated, show widespread genomic change, and are commonly BRCA-pathway disrupted.We sought to identify differences in genomic copy number changes between co-existing borderline and invasive components of serous carcinoma. Paired co-existing borderline and invasive tumor components were sampled and profiled from formalin-fixed paraffin embedded tumors from 6 patients

ORGANISM(S): Homo sapiens  

SUBMITTER: Dariush Etemadmoghadam   Catherine Emmanuel  Anna deFazio  Yoke-Eng Chiew  David Bowtell  Joshy George 

PROVIDER: E-GEOD-57276 | ArrayExpress | 2014-10-01

SECONDARY ACCESSION(S): GSE57276PRJNA246156

REPOSITORIES: GEO, ArrayExpress

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