Genomics

Dataset Information

62

Whole genome shotgun bisulfite sequencing of the Lsh-/- and Lsh+/+ murine embryonic fibroblasts and ES cells


ABSTRACT: Whole-genome single-base resolution methylcytosine map reveals profound changes that occur after Lsh deletion during embryonic development in primary WT and Lsh-/- MEFs. Lsh deletion leads to widespread decreases of CG methylation level at uniquely mapped genomic regions compared to wild type, including TSSs at protein-coding genes, and non-coding RNA genes. MethylC-Seq from Mus musculus primary MEFs.

ORGANISM(S): Mus musculus  

SUBMITTER: Jianke Ren   David Landsman  Kathrin Muegge  Robert Leighty  Joseph R Ecker  Carl McIntosh  Eunice Lee  Yixing Han  Ryan Lister  Weishi Yu  Minoru Terashima  Iris Zhu  Victorino Briones 

PROVIDER: E-GEOD-57486 | ArrayExpress | 2014-06-13

SECONDARY ACCESSION(S): SRP041823GSE57486

REPOSITORIES: GEO, ArrayExpress, ENA

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