Transcriptomics

Dataset Information

30

Exposure of rat to a variety of toxicants, heart assayed by Affymetrix microarray


ABSTRACT: DrugMatrix is a comprehensive rat toxicogenomics database and analysis tool developed to facilitate the integration of toxicogenomics into hazard assessment. Using the whole genome and a diverse set of compounds allows a comprehensive view of most pharmacological and toxicological questions and is applicable to other situations such as disease and development. Complete Drug Matrix dataset for rat heart. Approximately 600 different compounds were profiled in up to 7 different rat tissues by obtaining tissue samples from test compound-treated and vehicle control-treated rats in biological triplicates for gene expression analysis after 0.25, 1, 3, and 5 days of exposure with daily dosing. In a few studies (1.8%), 7 days of exposure was substituted for 5 days of exposure. Samples were hybridized to whole genome RG230_2.0 GeneChip arrays (Affymetrix, CA).

ORGANISM(S): Rattus norvegicus  

SUBMITTER: Scott Auerbach   

PROVIDER: E-GEOD-57800 | ArrayExpress| 2014-06-03

SECONDARY ACCESSION(S): GSE57800PRJNA248174

REPOSITORIES: GEO, ArrayExpress

altmetric image

Publications

Sorry, this publication's infomation has not been loaded in the Indexer, please go directly to PUBMED or Altmetric.

Similar Datasets

2014-06-04 | E-GEOD-57815 | ArrayExpress
2014-06-03 | E-GEOD-57816 | ArrayExpress
2014-06-03 | E-GEOD-57811 | ArrayExpress
2014-08-25 | E-GEOD-59894 | ArrayExpress
2014-08-24 | E-GEOD-59895 | ArrayExpress
2014-08-26 | E-GEOD-59905 | ArrayExpress
2014-08-25 | E-GEOD-59907 | ArrayExpress
2014-08-25 | E-GEOD-59913 | ArrayExpress
2014-08-23 | E-GEOD-59926 | ArrayExpress
2014-08-23 | E-GEOD-59925 | ArrayExpress