Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
DISEASE(S): Normal,Eosinophilic Esophagitis
SUBMITTER: Marc E Rothenberg Joseph D Sherrill Marc Rothenberg
PROVIDER: E-GEOD-58640 | ArrayExpress | 2014-06-27
SECONDARY ACCESSION(S): SRP043388GSE58640PRJNA253059
REPOSITORIES: GEO, ArrayExpress, ENA
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E-GEOD-58640.additional.1.zip | Other | |||
E-GEOD-58640.idf.txt | Idf | |||
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Sherrill J D JD Kiran K C KC Blanchard C C Stucke E M EM Kemme K A KA Collins M H MH Abonia J P JP Putnam P E PE Mukkada V A VA Kaul A A Kocoshis S A SA Kushner J P JP Plassard A J AJ Karns R A RA Dexheimer P J PJ Aronow B J BJ Rothenberg M E ME
Genes and immunity 20140612 6
Eosinophilic esophagitis (EoE) is an allergic inflammatory disorder of the esophagus that is compounded by genetic predisposition and hypersensitivity to environmental antigens. Using high-density oligonucleotide expression chips, a disease-specific esophageal transcript signature was identified and was shown to be largely reversible with therapy. In an effort to expand the molecular signature of EoE, we performed RNA sequencing on esophageal biopsies from healthy controls and patients with acti ...[more]