Transcriptomics

Dataset Information

34

Identification of targets genes of PRDM2 in G0 arrested myoblasts of C2C12


ABSTRACT: PRDM2 directly associates with the Myogenin promoter and repress its transcription. This led to the hypothesis that PRDM2 could potentially associate directly with other promoters and regulate their expression.To gain further insight into the pathways and genes controlled by PRDM2, ChIP-on-Chip analysis was performed using mouse 44K promoter array. Since PRDM2 represses transcription by H3K9 dimethylation, we were interested in determining which targets were occupied by PRDM2 as well as showed enrichment for H3K9me2. Hence ChIP-on-Chip analysis for H3K9me2 was performed to find the overlap between PRDM2 and H3K9me2 marked promoters. Agilent two-color ChIP-on-Chip experiment, Organism: Mus musculus ,Genotypic Technology designed Custom Mouse Promoter 244k ChIP-on-chip Array (AMADID-019046)

ORGANISM(S): Mus musculus  

SUBMITTER: Prethish Sreenivas  Amena Saleh   Henrik D Schroeder   Malini S Pillai   Deepika Puri   Mohammed Rumman   Genotypic technology   Jeeva Sellathurai   Jyotsna Dhawan   Sirisha Cheedipudi   Rakesh Mishra   Hardik Gala   Reety Arora    

PROVIDER: E-GEOD-58748 | ArrayExpress| 2015-08-19

SECONDARY ACCESSION(S): GSE58748PRJNA253333

REPOSITORIES: GEO, ArrayExpress

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