Transcriptomics

Dataset Information

1

MicroRNA expression profile in peri-implantation porcine embryos


ABSTRACT: Recently, microRNAs (miRNAs) have emerged as new players in the fine tuning of embryo development and implantation in mammals via posttranscriptional gene regulation mechanisms. Applying custom made multispecies arrays we aimed to analyze expression profile of microRNAs in peri-implantation porcine conceptuses/trophoblasts to identify their potential role at the maternal-fetal interface during the critical period of maternal recognition of pregnancy and implantation. miRNA expression profiles were analyzed in samples collected from embryos or trophoblast on Days 10, 11, 12, 16 and 20 of pregnancy. Each group was represented by five to nine samples.

ORGANISM(S): Sus scrofa  

SUBMITTER: Monika M Kaczmarek   Stefan Bauersachs  Kamil Krawczynski 

PROVIDER: E-GEOD-59618 | ArrayExpress | 2014-12-05

SECONDARY ACCESSION(S): GSE59618PRJNA255828

REPOSITORIES: GEO, ArrayExpress

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Publications

MicroRNAome of porcine conceptuses and trophoblasts: expression profile of micrornas and their potential to regulate genes crucial for establishment of pregnancy.

Krawczynski Kamil K   Najmula Joanna J   Bauersachs Stefan S   Kaczmarek Monika M MM  

Biology of reproduction 20141203 1


Tightly coordinated, reciprocal embryo-maternal interactions affect gene expression during early pregnancy. Recently, microRNAs (miRNAs) have emerged as new players in the fine tuning of embryo development and implantation in mammals via posttranscriptional gene regulation mechanisms. Here, we integrated transcriptomic and computational approaches to profile miRNAs and miRNA synthesis and transport-related genes at different developmental stages of porcine conceptuses and trophoblast during earl  ...[more]

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