Transcriptomics

Dataset Information

39

Effect of NDRG3 expression on cell response to hypoxia


ABSTRACT: Analysis of Huh-7 hepatocarcinoma cell line depleted of NDRG3 or HIF-1α under hypoxic condition. HIF-1α and NDRG3 have distinct functions in hypoxia responses. Results provide insight into molecular basis of HIF-independent signaling in the development and progression of hypoxic tumors Gene expression profiles of Huh-7 cells stably expressing NDRG3-shRNA or HIF-1α-shRNA under normoxia were compared to gene expression profiles of Huh-7 stable cells under hypoxia for 3, 6, 12 and 24 hours.

ORGANISM(S): Homo sapiens  

SUBMITTER: Minho Kang  Suk-Jin Yang   Young I Yeom   Dong C Lee    

PROVIDER: E-GEOD-59729 | ArrayExpress | 2015-08-19

SECONDARY ACCESSION(S): GSE59729PRJNA256092

REPOSITORIES: GEO, ArrayExpress

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