Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Francesco Neri Salvatore Oliviero Federica Collino Daniela Dettori Peter Quesenberry Ciro Tetta Danny Incarnato Giovanni Camussi Stefania Bruno
PROVIDER: E-GEOD-59958 | ArrayExpress | 2015-05-07
SECONDARY ACCESSION(S): GSE59958SRP045150PRJNA257193
REPOSITORIES: GEO, ArrayExpress, ENA
Collino Federica F Bruno Stefania S Incarnato Danny D Dettori Daniela D Neri Francesco F Provero Paolo P Pomatto Margherita M Oliviero Salvatore S Tetta Ciro C Quesenberry Peter J PJ Camussi Giovanni G
Journal of the American Society of Nephrology : JASN 20150421 10
Phenotypic changes induced by extracellular vesicles have been implicated in mesenchymal stromal cell-promoted recovery of AKI. MicroRNAs are potential candidates for cell reprogramming toward a proregenerative phenotype. The aim of this study was to evaluate whether microRNA deregulation inhibits the regenerative potential of mesenchymal stromal cells and derived extracellular vesicles in a model of glycerol-induced AKI in severe combined immunodeficient mice. We generated mesenchymal stromal c ...[more]