Dataset Information


Human embryonic stem cells

ABSTRACT: Undifferentiated human embryonic stem cells grown on mouse embryonic fibroblast feeder layers. HES3 and HES4 are proprietary human ES cell lines of ES Cell International Pte Ltd. Singapore. Keywords: other

ORGANISM(S): Homo sapiens  

SUBMITTER: Woon-Khiong Chan   Mark Richards 

PROVIDER: E-GEOD-608 | ArrayExpress | 2004-01-18



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The transcriptome profile of human embryonic stem cells as defined by SAGE.

Richards Mark M   Tan Siew-Peng SP   Tan Jee-Hian JH   Chan Woon-Khiong WK   Bongso Ariff A  

Stem cells (Dayton, Ohio) 20040101 1

Human embryonic stem (ES) cell lines that have the ability to self-renew and differentiate into specific cell types have been established. The molecular mechanisms for self-renewal and differentiation, however, are poorly understood. We determined the transcriptome profiles for two proprietary human ES cell lines (HES3 and HES4, ES Cell International), and compared them with murine ES cells and other human tissues. Human and mouse ES cells appear to share a number of expressed gene products alth  ...[more]

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