Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA262584PRJNA262585PRJNA262583PRJNA262587PRJNA262586
ORGANISM(S): Mus musculus
SUBMITTER: Robert S Young David A Hume Wendy A Bickmore Alasdair W Jubb
PROVIDER: E-GEOD-61879 | ArrayExpress | 2015-12-17
SECONDARY ACCESSION(S): GSE61879PRJNA262585
REPOSITORIES: GEO, ArrayExpress
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E-GEOD-61879.idf.txt | Idf | |||
E-GEOD-61879.processed.1.zip | Processed | |||
E-GEOD-61879.raw.1.zip | Raw | |||
E-GEOD-61879.sdrf.txt | Txt |
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Jubb Alasdair W AW Young Robert S RS Hume David A DA Bickmore Wendy A WA
Journal of immunology (Baltimore, Md. : 1950) 20151209 2
Phenotypic differences between individuals and species are controlled in part through differences in expression of a relatively conserved set of genes. Genes expressed in the immune system are subject to especially powerful selection. We have investigated the evolution of both gene expression and candidate enhancers in human and mouse macrophages exposed to glucocorticoid (GC), a regulator of innate immunity and an important therapeutic agent. Our analyses revealed a very limited overlap in the ...[more]