Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA97535
INSTRUMENT(S): 418 [Affymetrix]
SUBMITTER: Ezequiel L. Calvo
PROVIDER: E-GEOD-6219 | ArrayExpress | 2007-11-14
SECONDARY ACCESSION(S): GDS2638GSE6219PRJNA97535
REPOSITORIES: GEO, ArrayExpress
Action | DRS | |||
---|---|---|---|---|
E-GEOD-6219.README.txt | Txt | |||
E-GEOD-6219.eSet.r | Other | |||
E-GEOD-6219.idf.txt | Idf | |||
E-GEOD-6219.processed.1.zip | Processed | |||
E-GEOD-6219.raw.1.zip | Raw |
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Physiological genomics 20070301 1
17beta-Estradiol (E2) is well known to be associated with uterine cancer, endometriosis, and leiomyomas. Although insulin-like growth factor I (IGF-I) has been identified as a mediator of the uterotrophic effect of E2 in several studies, this mechanism is still not well understood. In the present study, identification of the genes modulated by a physiological dose of E2, in the uterus, has been done in ovariectomized mice using Affymetrix microarrays. The E2-induced genomic profile shows that mu ...[more]