Transcriptomics

Dataset Information

3

LT2_MitomycinC_2ug/ml_RNA

ABSTRACT: Gene expression of Salmonella enterica sv Typhimurium LT2 post treatment with 2ug/ml mitomycin C.

SUBMITTER: Jonathan G Frye  Steffen Porwollik  Felisa Blackmer  Pui Cheng  Michael McClelland 

PROVIDER: E-GEOD-622 | ArrayExpress | 2010-06-09

SECONDARY ACCESSION(S): GSE622PRJNA87525

REPOSITORIES: GEO, ArrayExpress

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Publications

Host gene expression changes and DNA amplification during temperate phage induction.

Frye Jonathan G JG   Porwollik Steffen S   Blackmer Felisa F   Cheng Pui P   McClelland Michael M  

Journal of bacteriology 20050201 4

Salmonella enterica serovar Typhimurium LT2 harbors four temperate prophages. The lytic cycle of these phages was induced with hydrogen peroxide or mitomycin C. Microarray analysis was used to monitor the increase in phage genome copy number and the changes in RNA expression. Phage gene transcription was classified temporally, and host genes that responded to hydrogen peroxide, mitomycin C, or phage induction were also identified. A region of the serovar Typhimurium LT2 host genome encompassing  ...[more]

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