Transcriptomics

Dataset Information

2

Differential expression of mRNAs in naïve, effector, and memory CD8 T cells of mir-150 KO and wild-type mice


ABSTRACT: microRNA-150 (miR-150) is mainly expressed in the lymph nodes and spleen and is highly up-regulated during the development of mature T and B cells. To understand the signal-transduction network for 'effector or memory T cells' and 'mir-150' in naïve, effector, or memory CD8 T cells of mir-150 knockout and wild-type mice, we analyzed gene expression profiles by microarray. The genetic background of the cells used in this study is CD8 T cells from spleen of the 8 week-old male C57BL/6J mice (for female: WT-memory_2 & KO-memory_2). Corresponding authors: Inpyo Choi, PhD, Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro,Yuseong, Daejeon 305-806, Republic of Korea. E-mail: ipchoi@kribb.re.kr. Or: Tae-Don Kim, PhD, Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong, Daejeon 305-806, Republic of Korea. E-mail: tdkim@kribb.re.kr. wild-type[WT] vs. mir-150 knockout[KO]; naïve, effector, and memory CD8 T cells.

ORGANISM(S): Mus musculus  

SUBMITTER: Jung Min Kim   Inpyo Choi  Jung M Kim  Tae-Don Kim 

PROVIDER: E-GEOD-62262 | ArrayExpress | 2014-10-11

SECONDARY ACCESSION(S): GSE62262PRJNA263596

REPOSITORIES: GEO, ArrayExpress

Dataset's files

Source:
Action DRS
E-GEOD-62262.idf.txt Idf
E-GEOD-62262.processed.1.zip Processed
E-GEOD-62262.raw.1.zip Raw
E-GEOD-62262.sdrf.txt Txt
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