Transcriptomics

Dataset Information

38

SL1344_hydrogen_peroxide_2mM_DNA


ABSTRACT: Gene content in Salmonella enterica sv Typhimurium SL1344 post treatment with 2mM hydrogen peroxide

ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium  

SUBMITTER: Jonathan G Frye   Steffen Porwollik   Felisa Blackmer   Pui Cheng   Michael McClelland  

PROVIDER: E-GEOD-625 | ArrayExpress | 2012-03-27

SECONDARY ACCESSION(S): GSE625PRJNA87531

REPOSITORIES: GEO, ArrayExpress

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Publications

Host gene expression changes and DNA amplification during temperate phage induction.

Frye Jonathan G JG   Porwollik Steffen S   Blackmer Felisa F   Cheng Pui P   McClelland Michael M  

Journal of bacteriology 20050201 4


Salmonella enterica serovar Typhimurium LT2 harbors four temperate prophages. The lytic cycle of these phages was induced with hydrogen peroxide or mitomycin C. Microarray analysis was used to monitor the increase in phage genome copy number and the changes in RNA expression. Phage gene transcription was classified temporally, and host genes that responded to hydrogen peroxide, mitomycin C, or phage induction were also identified. A region of the serovar Typhimurium LT2 host genome encompassing  ...[more]

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