Transcriptomics

Dataset Information

81

Polysome profiling of glp-4 mutant animals


ABSTRACT: To determine the translational status of mRNAs in glp-4 mutant animals, we analyzed total and polysomal RNA levels by tiling arrays A total of 8 samples was analyzed (quadruplicates of glp-4_total and glp-4_polysomal, respectively)

ORGANISM(S): Caenorhabditis elegans  

SUBMITTER: Dimos Gaidatzis  Claudia Scheckel   Jane E Wright   Stephane Thiry   Rafal Ciosk    

PROVIDER: E-GEOD-62860 | ArrayExpress| 2015-01-09

SECONDARY ACCESSION(S): GSE62860PRJNA265856

REPOSITORIES: GEO, ArrayExpress

altmetric image

Publications

Functional characterization of C. elegans Y-box-binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes.

Arnold Andreas A   Rahman Md Masuder MM   Lee Man Chun MC   Muehlhaeusser Sandra S   Katic Iskra I   Gaidatzis Dimos D   Hess Daniel D   Scheckel Claudia C   Wright Jane E JE   Stetak Attila A   Boag Peter R PR   Ciosk Rafal R  

Nucleic acids research 20141105 21


The cold shock domain is one of the most highly conserved motifs between bacteria and higher eukaryotes. Y-box-binding proteins represent a subfamily of cold shock domain proteins with pleiotropic functions, ranging from transcription in the nucleus to translation in the cytoplasm. These proteins have been investigated in all major model organisms except Caenorhabditis elegans. In this study, we set out to fill this gap and present a functional characterization of CEYs, the C. elegans Y-box-bind  ...[more]

Similar Datasets

2012-07-24 | E-GEOD-33083 | ArrayExpress
2015-01-09 | E-GEOD-62861 | ArrayExpress
2016-01-02 | E-GEOD-56427 | ArrayExpress
2014-01-20 | E-GEOD-46544 | ArrayExpress
2014-06-03 | E-GEOD-46273 | ArrayExpress
2003-12-31 | GSE716 | GEO
2003-12-31 | GSE715 | GEO
2003-12-31 | GSE718 | GEO
2003-12-31 | GSE717 | GEO
| GSE64024 | GEO