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Functional characterization of C. elegans Y-box binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Caenorhabditis elegans  

SUBMITTER: Dimos Gaidatzis  

PROVIDER: E-GEOD-62861 | ArrayExpress | 2015-01-08



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Functional characterization of C. elegans Y-box-binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes.

Arnold Andreas A   Rahman Md Masuder MM   Lee Man Chun MC   Muehlhaeusser Sandra S   Katic Iskra I   Gaidatzis Dimos D   Hess Daniel D   Scheckel Claudia C   Wright Jane E JE   Stetak Attila A   Boag Peter R PR   Ciosk Rafal R  

Nucleic acids research 20141105 21

The cold shock domain is one of the most highly conserved motifs between bacteria and higher eukaryotes. Y-box-binding proteins represent a subfamily of cold shock domain proteins with pleiotropic functions, ranging from transcription in the nucleus to translation in the cytoplasm. These proteins have been investigated in all major model organisms except Caenorhabditis elegans. In this study, we set out to fill this gap and present a functional characterization of CEYs, the C. elegans Y-box-bind  ...[more]

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