Transcriptomics

Dataset Information

4

A genomic landscape of enhanced bovine pluripotency


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Bos taurus  

SUBMITTER: Marian Groot Koerkamp  

PROVIDER: E-GEOD-63054 | ArrayExpress | 2015-05-07

SECONDARY ACCESSION(S): GSE63054PRJNA266517

REPOSITORIES: GEO, ArrayExpress

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Publications

A mRNA landscape of bovine embryos after standard and MAPK-inhibited culture conditions: a comparative analysis.

Brinkhof Bas B   van Tol Helena T A HT   Groot Koerkamp Marian J A MJ   Riemers Frank M FM   IJzer Sascha G SG   Mashayekhi Kaveh K   Haagsman Henk P HP   Roelen Bernard A J BA  

BMC genomics 20150410


Genes and signalling pathways involved in pluripotency have been studied extensively in mouse and human pre-implantation embryos and embryonic stem (ES) cells. The unsuccessful attempts to generate ES cell lines from other species including cattle suggests that other genes and pathways are involved in maintaining pluripotency in these species. To investigate which genes are involved in bovine pluripotency, expression profiles were generated from morula, blastocyst, trophectoderm and inner cell m  ...[more]

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