Transcriptomics,Genomics,Multiomics

Dataset Information

89

Ets homologous factor regulates pathways controlling response to injury in Calu-3 airway epithelial cells


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens  

SUBMITTER: Ann Harris   

PROVIDER: E-GEOD-63400 | ArrayExpress | 2015-01-02

SECONDARY ACCESSION(S): GSE63400PRJNA267656

REPOSITORIES: GEO, ArrayExpress

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Publications

Ets homologous factor regulates pathways controlling response to injury in airway epithelial cells.

Fossum Sara L SL   Mutolo Michael J MJ   Yang Rui R   Dang Hong H   O'Neal Wanda K WK   Knowles Michael R MR   Leir Shih-Hsing SH   Harris Ann A  

Nucleic acids research 20141120 22


Ets homologous factor (EHF) is an Ets family transcription factor expressed in many epithelial cell types including those lining the respiratory system. Disruption of the airway epithelium is central to many lung diseases, and a network of transcription factors coordinates its normal function. EHF can act as a transcriptional activator or a repressor, though its targets in lung epithelial cells are largely uncharacterized. Chromatin immunoprecipitation followed by deep sequencing (ChIP-seq), sho  ...[more]

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