Dataset Information


Ets homologous factor regulates pathways controlling response to injury in Calu-3 airway epithelial cells

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens  

SUBMITTER: Ann Harris  

PROVIDER: E-GEOD-63400 | ArrayExpress | 2014-12-23



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Ets homologous factor regulates pathways controlling response to injury in airway epithelial cells.

Fossum Sara L SL   Mutolo Michael J MJ   Yang Rui R   Dang Hong H   O'Neal Wanda K WK   Knowles Michael R MR   Leir Shih-Hsing SH   Harris Ann A  

Nucleic acids research 20141120 22

Ets homologous factor (EHF) is an Ets family transcription factor expressed in many epithelial cell types including those lining the respiratory system. Disruption of the airway epithelium is central to many lung diseases, and a network of transcription factors coordinates its normal function. EHF can act as a transcriptional activator or a repressor, though its targets in lung epithelial cells are largely uncharacterized. Chromatin immunoprecipitation followed by deep sequencing (ChIP-seq), sho  ...[more]

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