Transcriptomics

Dataset Information

3

Global gene expression profiling of primary tumors and lung metastases using a mouse model of spontaneous metastatic mammary carcinoma


ABSTRACT: In this study, we explored the molecular basis of site-specific metastasis of breast cancer to the lungs in a clinically relevant model based on the JygMC(A) cell line. In this dataset, we include expression data from JygMC(A) primary mammary tumors, lung metastases, normal mammary glands and normal lung parenchyma. In total, 28 samples were analyzed. We generated the following pairwise comparisons using Partek Genomic Suite 6.6 (PGS, Version 6.6, Partek Inc.): PT vs. NMG; PT vs. LM; LM vs. NL; LM vs. NMG. Genes with an FDR-adjusted p-value < 0.05 and a fold-change > 2 were selected.

ORGANISM(S): Mus musculus  

SUBMITTER: Nadia Pereira de Castro   Anand Merchant  David Salomon  Natalie Abrams 

PROVIDER: E-GEOD-63627 | ArrayExpress | 2015-11-02

SECONDARY ACCESSION(S): GSE63627PRJNA268496

REPOSITORIES: GEO, ArrayExpress

Similar Datasets

2014-10-01 | E-GEOD-53482 | ArrayExpress
2015-09-30 | E-MTAB-2977 | ArrayExpress
2014-05-15 | E-GEOD-53965 | ArrayExpress
2013-01-12 | E-GEOD-43445 | ArrayExpress
2013-08-01 | E-GEOD-48351 | ArrayExpress
2015-08-07 | E-GEOD-71783 | ArrayExpress
2016-03-31 | E-GEOD-79737 | ArrayExpress
| GSE43445 | GEO
2015-11-11 | E-GEOD-63296 | ArrayExpress
2014-11-04 | E-GEOD-53105 | ArrayExpress