Transcriptomics

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Transcriptional profiling of microdissected ventromedial hypothalamus in Nkx2-1 f/f vs. Nkx2-1 f/f; Sf1Cre female mice


ABSTRACT: Microdissected ventromedial hypothalamus (VMH) was profiled to identify transcriptional changes after Nkx2-1 ablation in female mice. Total RNA was extracted from conditional mutants (Nkx2-1 f/f; Sf1Cre) and floxed controls (Nkx2-1 f/f) at postnatal day 10 (P10) and profiled using Mouse ref8 v2.0 Illumina chips and reagents (n=4/group). The tissue profiled is microdissected ventromedial hypothalamus from P10 female mice. Controls and mutants are analyzed in quadruplicate.

ORGANISM(S): Mus musculus  

SUBMITTER: Pierre Flandin   James P Warne  David W Newstrom  Allison W Xu  Stephanie M Correa  John L Rubenstein  Holly A Ingraham  Alexander T Lin-Moore  Andrew A Pierce  Clement C Cheung  Giovanni Coppola 

PROVIDER: E-GEOD-63656 | ArrayExpress | 2014-11-27

SECONDARY ACCESSION(S): GSE63656PRJNA268579

REPOSITORIES: GEO, ArrayExpress

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