Transcriptomics

Dataset Information

40

Expression data from the orthotopic tumors of MES-SA


ABSTRACT: The spontaneous pulmonary metastasis model of human uterine sarcoma was established using GFP-expressed MES-SA cells. Several sublines with different metastatic potentials were generated by in vivo passaging. We used microarrays to identify the metastatic-related genes using the orthotopic tumors with different metastatic potentials. Orthotopic transplanted uterine sarcoma were observed after 3 weeks post-transplantation and the xenografted tumor reached about 2000 mm3 in additional 3 weeks. After 6 weeks post-transplantation, the animals were sacrificed under isoflurane anesthesia, and the tumors were resected. The GFP-positive regions were collected using Leica MZ10F fluorescent stereomicroscope. This study compared the gene expression profiling between the orthotopic tumors with high (H)- and low (L)-metastatic potentials.

ORGANISM(S): Homo sapiens  

SUBMITTER: Tetsuya Mizutani  Shin Ishikane   Kaoru Miyamoto   Shinya Kawabe    

PROVIDER: E-GEOD-63937 | ArrayExpress | 2015-01-02

SECONDARY ACCESSION(S): GSE63937PRJNA269568

REPOSITORIES: GEO, ArrayExpress

altmetric image

Publications

Sorry, this publication's infomation has not been loaded in the Indexer, please go directly to PUBMED or Altmetric.

Similar Datasets

2016-02-22 | E-GEOD-71677 | ArrayExpress
2013-06-18 | E-GEOD-47554 | ArrayExpress
2012-06-25 | E-GEOD-33200 | ArrayExpress
2015-08-17 | E-GEOD-30812 | ExpressionAtlas
| GSE88826 | GEO
2015-08-12 | E-GEOD-30812 | ArrayExpress
2011-06-10 | E-GEOD-27515 | ArrayExpress
2011-05-25 | GSE27515 | GEO
2018-02-07 | PXD007909 | Pride
2015-02-08 | E-GEOD-64771 | ArrayExpress