Dataset Information


Expression data from Drd1a and Drd2 expressing neurons in striatum and cortex, at 6 weeks and 2 years of age

ABSTRACT: We performed a study of gene expression changes that occur during mouse aging in the striatum and cortex in specific neuronal populations. Using translating ribosome afifnity purificaiton, we captured cell type-specific mRNAs from Drd1a-expressing cortical neurons, Drd1a-expressing striatal neurons, Drd2-expressing cortical neurons, and Drd2-expressing striatal neurons. 31 total samples were anlayzed. We generated the followinf pairwise comparisons: Old (2 years) vs young (6 weeks) Drd1a expressing cortical cells; old (2 years) vs young (6 weeks) Drd2 expressing cortical cells; old (2 years) vs young (6 weeks) Drd1a expressing striatal cells; old (2 years) vs young (6 weeks) Drd2 expressing striatal cells. We used a restriction of Benjamini-Hochberg FDR <0.05, and a fold-change restriction of 1.2-fold.

ORGANISM(S): Mus musculus  

SUBMITTER: Myriam Heiman  R Shema   M Heiman    

PROVIDER: E-GEOD-64140 | ArrayExpress | 2015-01-02



altmetric image


Sorry, this publication's infomation has not been loaded in the Indexer, please go directly to PUBMED or Altmetric.

Similar Datasets

2014-06-03 | E-GEOD-55096 | ArrayExpress
| PRJNA270240 | ENA
2010-05-01 | GSE20547 | GEO
2014-05-01 | E-GEOD-20547 | ArrayExpress
2012-11-08 | E-GEOD-41638 | ArrayExpress
2014-05-03 | E-MEXP-3878 | ArrayExpress
| GSE87758 | GEO
2018-08-30 | GSE119183 | GEO
| PRJNA133491 | ENA
2012-04-03 | E-GEOD-1371 | ArrayExpress