Transcriptomics

Dataset Information

2

Genome-wide analysis of MCF-7 cells expressing or not MMP-14 (MT1-MMP) growing in monolayer cell culture conditions


ABSTRACT: In order to investigate the impact of MMP-14 (MT1-MMP) on the transcriptomes of a human breast adenocarcinoma cell line, we performed a microarray analysis from RNAs isolated from MCF-7 cells expressing either an empty vector (VEC) or human MMP-14 cDNA (MT1) in monolayer growth conditions. MCF-7 cells were stably transfected with either an empty vector (pcDNA3.1/Zeo) or human MMP-14 cDNA (pcDNA3.1-MMP-14/Zeo). Cells were grown for 48 hours in monolayer culture. Cells were then lysed in TRIzol and total RNA was isolated. For each experimental condition, total RNAs isolated from 3 independant biological replicates were pooled.

ORGANISM(S): Homo sapiens  

SUBMITTER: Erik Maquoi   Agnès Noël 

PROVIDER: E-GEOD-64320 | ArrayExpress | 2015-12-11

SECONDARY ACCESSION(S): GSE64320PRJNA270746

REPOSITORIES: GEO, ArrayExpress

Dataset's files

Source:
Action DRS
E-GEOD-64320.idf.txt Idf
E-GEOD-64320.processed.1.zip Processed
E-GEOD-64320.raw.1.zip Raw
E-GEOD-64320.sdrf.txt Txt
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