Genome-wide mapping of DNA hydroxymethylation in osteoarthritic chondrocytes [methylation]
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ABSTRACT: Examination of the genome-wide distribution of 5hmC in osteoarthritic chondrocytes compared to normal chondrocytes in order to elucidate the effect on OA-specific gene expression. 5hmC-sequencing was performed and data was compared with microarray gene expression data to identify genes with differential expression between normal and OA chondrocytes that are potentially under epigenetic regulation. High-throughput sequencing of 5hmC in 4 normal and 4 OA chondrocyte samples.
ORGANISM(S): Homo sapiens
SUBMITTER:
Ye H Li Nidhi Bhutani Sarah E Taylor Wing H Wong Sarah EB Taylor
PROVIDER: E-GEOD-64393 | ArrayExpress | 2015-06-30
SECONDARY ACCESSION(S): SRP051399GSE64393PRJNA270885
REPOSITORIES: GEO, ArrayExpress, ENA
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