Dataset Information


Extremely low frequency electromagnetic fields enhance neuronal differentiation of human mesenchymal stem cells on graphene-based substrate

ABSTRACT: Graphene-based substrate has efficient neuronal differentiation of hMSCs. Stimulatory effects of graphene on hMSCs neurogenesis can be enhanced by ELF-EMF exposure and it is mediated by enhancement of cell adhesion accompanied by intracellular signal pathway. We used microarrays to assess up-regulated genes in human gene expression profiles during neurogenesis induced by ELF-EMF exposure on graphene. 3 groups (HMSCs grown in neuronal medium on glass, graphene, graphene under ELF-EMF exposure) were selected for RNA extraction and hybridization on Affymetrix microarrays. We sought to obtain total human gene expression. To that end, we hand-selected up-regulated gene involved in neurogenesis, extracellular matrix, and cell migration.

ORGANISM(S): Homo sapiens  

SUBMITTER: Yoojung Lee   YooJung Lee 

PROVIDER: E-GEOD-64416 | ArrayExpress | 2014-12-23



Similar Datasets

2014-03-29 | E-GEOD-45631 | ArrayExpress
2015-12-31 | E-GEOD-57298 | ArrayExpress
2012-11-01 | E-GEOD-35999 | ArrayExpress
| GSE35999 | GEO
| GSE3421 | GEO
2012-10-31 | E-GEOD-37833 | ArrayExpress
2016-07-01 | E-GEOD-71147 | ArrayExpress
2011-02-15 | E-GEOD-27308 | ArrayExpress
2010-07-20 | E-GEOD-22991 | ArrayExpress
2011-02-15 | GSE27308 | GEO