Transcriptomics

Dataset Information

6

Expression data from H295R_GRα cells following treatment with dexamethasone or RU486


ABSTRACT: The human glucocorticoid receptor (GRα) is overexpressed at the molecular and protein level in malignant human adrenocortical cancers. A stable cell line model of GRα overexpression was established using the H295R human adrenocortical cancer cell line. The following results were obtained from gene expression profiling of H295R_GRα and H295R_Control (empty vector) cells following treatment with either a GRα agonist (dexamethasone), GRα antagonist (RU486) or vehicle (ethanol) control. H295R_GRα and H295R_Control (empty vector) cells were treated in triplicate for 6 hours with dexamethasone 100 nM, RU486 100 nM or vehicle (ethanol) control.

ORGANISM(S): Homo sapiens  

SUBMITTER: Lyndal Tacon   Roderick Clifton-Bligh 

PROVIDER: E-GEOD-64826 | ArrayExpress | 2015-01-10

SECONDARY ACCESSION(S): GSE64826PRJNA272128

REPOSITORIES: GEO, ArrayExpress

Similar Datasets

2013-02-05 | E-GEOD-39654 | ArrayExpress
2013-01-09 | E-GEOD-39270 | ArrayExpress
2007-03-22 | GSE6509 | GEO
2014-05-21 | E-GEOD-49804 | ArrayExpress
2015-07-27 | E-GEOD-49804 | ExpressionAtlas
2012-04-29 | E-GEOD-33753 | ArrayExpress
2008-08-21 | GSE11791 | GEO
2008-10-25 | E-GEOD-11791 | ArrayExpress
2011-07-22 | E-GEOD-30871 | ArrayExpress
2012-09-11 | E-GEOD-40725 | ArrayExpress