Genomics

Dataset Information

296

Chronic growth factor signaling in Acute Myeloid Leukemia is connected to a specific chromatin signature [DNAse-Seq]


ABSTRACT: We performed genome-wide DNaseI hypersensitive site in FLT3-ITD and WT patient samples. We report corresponding gene expression, promoter methylation patterns of differential DHSs as well as differentially occupied TF binding motifs using surrounding DNAseI cut profiles. We examined association patterns of FLT3 ITD and WT AMLs and found that FLT3-ITD signaling is associated with common gene expression and chromatin signature. Examination of genome-wide DNaseI hypersensitivite sites in FLT3 ITD and WT AML.

ORGANISM(S): Homo sapiens  

SUBMITTER: Anetta Ptasinska   Maria R Imperato  Salam Assi  Joaquin Zacarias-Cabeza  Pierre Daniel Cauchy  Peter Cockerill  Sascha Ott  Sally James  Constanze Bonifer  Jason Piper 

PROVIDER: E-GEOD-64864 | ArrayExpress | 2015-07-03

SECONDARY ACCESSION(S): GSE64864SRP052030PRJNA272427

REPOSITORIES: GEO, ArrayExpress, ENA

Similar Datasets

2015-07-03 | E-GEOD-64862 | ArrayExpress
2014-09-24 | E-GEOD-51726 | ArrayExpress
2018-05-31 | E-MTAB-6682 | ArrayExpress
2015-07-03 | E-GEOD-64934 | ArrayExpress
2015-07-03 | E-GEOD-64873 | ArrayExpress
2011-07-25 | E-GEOD-30902 | ArrayExpress
2014-11-06 | E-GEOD-58448 | ArrayExpress
2014-02-13 | E-GEOD-37560 | ArrayExpress
2017-05-02 | PXD004442 | Pride
2015-11-20 | E-GEOD-75200 | ArrayExpress