Transcriptomics

Dataset Information

3

MiR-30e in Aortic Smooth Muscle Cells and Bone Marrow Mesenchymal Stem Cells [Experiment 3]


ABSTRACT: MiR-30e represses the osteogenic program in mesenchymal stem cells (MSCs) and smooth muscle cells (SMCs) by targeting IGF2, and drives their differentiation into adipogenic or smooth muscle lineage, respectively. In Experiment 1, SMCs were cultured from mouse aortas and transduced with miR-30e or control lentivirus. In Experiment 2, MSCs were extracted from mouse bone marrow and transduced with miR-30e or control lentivirus. In Experiment 3, the MSCs were transfected with a scrambled oligo or anti-miR-30e oligo. In all 3 experiments, N=3 per group. RNA was extracted from each experiment and run on Affymetrix arrays.

ORGANISM(S): Mus musculus  

SUBMITTER: Lina A Shehadeh   Lina Shehadeh 

PROVIDER: E-GEOD-65434 | ArrayExpress | 2015-01-30

SECONDARY ACCESSION(S): GSE65434PRJNA273990

REPOSITORIES: GEO, ArrayExpress

Similar Datasets

2015-01-30 | E-GEOD-65431 | ArrayExpress
2015-01-30 | E-GEOD-65432 | ArrayExpress
2015-01-01 | S-EPMC4375408 | BioStudies
1000-01-01 | S-EPMC5971462 | BioStudies
2019-01-01 | S-EPMC6825513 | BioStudies
2012-01-01 | S-EPMC3516396 | BioStudies
2010-02-17 | GSE20293 | GEO
2012-01-01 | S-EPMC3251334 | BioStudies
2011-01-01 | S-EPMC3207238 | BioStudies
2014-01-01 | S-EPMC4280132 | BioStudies