Transcriptomics

Dataset Information

1

Gata6 induced XEN-like cells w/o Sox7


ABSTRACT: To understand the role of Sox7 in primitive endoderm differentiation, we compare the gene expression pattern of Sox7 (+/-) and Sox7 (-/-) ES cells with or without dexamethasome (Dex) treatment. Because these ES cells harbour Gata6-GR transgene, Dex treatment forces ES cells differentate into XEN-like cells. As Sox7 (-/-) ES cells can differentiate into XEN-like cell by morphology, we assessed genome wide gene expression pattern. Sox7 (+/-) ES cells and Sox7 (-/-) ES cells are forced to differentiate into XEN-like cells by Gata6-GR transgene. To compare the gene expression, we collected RNA samples at day4 with or without dexamethasone treatment from each genotype.

ORGANISM(S): Mus musculus  

SUBMITTER: Hitoshi Niwa   Masaki Kinoshita  Mariko Yamane 

PROVIDER: E-GEOD-66971 | ArrayExpress | 2015-09-14

SECONDARY ACCESSION(S): GSE66971PRJNA278525

REPOSITORIES: GEO, ArrayExpress

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