Transcriptomics

Dataset Information

35

Array of CCR6+ ILC3 from the mesenteric lymph node of naïve C57BL/6 mice


ABSTRACT: CCR6+ innate lymphoid cells were sorted from the mesenteric lymph node of naïve C57BL/6 mice Cells were sort purified as lineage negative, CD127+ CD90.2+ CCR6+ ST2- 4 replicates were performed

ORGANISM(S): Mus musculus  

SUBMITTER: Gregory F Sonnenberg   

PROVIDER: E-GEOD-67076 | ArrayExpress| 2015-05-23

SECONDARY ACCESSION(S): GSE67076PRJNA278866

REPOSITORIES: GEO, ArrayExpress

altmetric image

Publications


Inflammatory CD4(+) T cell responses to self or commensal bacteria underlie the pathogenesis of autoimmunity and inflammatory bowel disease (IBD), respectively. Although selection of self-specific T cells in the thymus limits responses to mammalian tissue antigens, the mechanisms that control selection of commensal bacteria-specific T cells remain poorly understood. Here, we demonstrate that group 3 innate lymphoid cell (ILC3)-intrinsic expression of major histocompatibility complex class II (MH  ...[more]

Similar Datasets

2016-02-21 | E-GEOD-76201 | ArrayExpress
2013-07-17 | E-GEOD-36482 | ArrayExpress
2014-06-07 | E-GEOD-58145 | ArrayExpress
2012-03-27 | E-GEOD-21041 | ArrayExpress
2016-08-24 | E-MTAB-4839 | ArrayExpress
2013-05-07 | E-GEOD-46468 | ArrayExpress
2012-03-27 | E-GEOD-15750 | ArrayExpress
2010-06-11 | GSE22311 | GEO
2014-06-02 | E-GEOD-44663 | ArrayExpress
2016-09-12 | E-GEOD-72733 | ArrayExpress