Genomics

Dataset Information

6

Histone architecture of stem-cell memory T cells reveals progressive remodeling of epigenetic landscape in antigen-experienced CD8 T cells


ABSTRACT: We investigated the genomic landscape of histone modifications in antigen-experienced CD8+ T cells. Using a ChIP-Seq approach coupled with global gene expression profiling [GSE67825], we generated genome-wide histone H3 lysine 4 (H3K4me3) and H3 lysine 27 (H3K27me3) trimethylation maps in distinct subsets of CD8+ T cells - naïve, stem cell memory, central memory, and effector memory. To gain insight into how histone architecture is remodeled during the differentiation of activated T cells

ORGANISM(S): Mus musculus  

SUBMITTER: Nicholas Restifo   Joseph G Crompton  Manikandan Narayanan 

PROVIDER: E-GEOD-67881 | ArrayExpress | 2015-04-15

SECONDARY ACCESSION(S): SRP057167GSE67881PRJNA281104

REPOSITORIES: GEO, ArrayExpress, ENA

Dataset's files

Source:
Action DRS
E-GEOD-67881.idf.txt Idf
E-GEOD-67881.processed.1.zip Processed
E-GEOD-67881.sdrf.txt Txt
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