Transcriptomics

Dataset Information

299

Phosphorylation events in the Multiple Gene Regulator of Group A Streptococcus (Mga) Significantly Influences Global Gene Expression and Virulence.


ABSTRACT: We sought understand the molecular mehcanism of gene regulation by Mga and its contribution to GAS pathogenesis in serotype M59 GAS through whole transcriptome analysis of strains with phosphorylation mimicking substitutions in key histidine residues of Mga. There were 6 strains analyzed, each in triplicate replicates: 1)wild-type GAS, 2)mga deletion strain 3)mga with alanine at H207 4)mga with aspartate at H207, 5) mga with alanine at H273 6)mga with aspartate at H273

ORGANISM(S): Streptococcus pyogenes MGAS15252  

SUBMITTER: Misu Sanson   Randall J Olsen  Randall Olsen  Muthiah Kumaraswami 

PROVIDER: E-GEOD-67988 | ArrayExpress | 2015-04-18

SECONDARY ACCESSION(S): GSE67988SRP057294PRJNA281450

REPOSITORIES: GEO, ArrayExpress, ENA

Similar Datasets

2005-04-06 | GSE1895 | GEO
2006-08-31 | GSE4596 | GEO
2006-08-31 | GSE4598 | GEO
2006-08-31 | GSE4597 | GEO
2015-01-24 | E-GEOD-65226 | ArrayExpress
2013-08-21 | E-GEOD-43408 | ArrayExpress
| PRJNA90981 | ENA
2016-03-02 | E-GEOD-77721 | ArrayExpress
2013-12-03 | E-GEOD-52867 | ArrayExpress
2015-04-06 | E-GEOD-64448 | ArrayExpress