Transcriptomics

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Gene expression profiling in Abatacept treated Rheumatoid Arthritis patients according to response


ABSTRACT: The objective of this study was to identify specific gene expression profiles able to predict the response of rheumatoid arthritis patients treated with methotrexate /abatacept (Aba). Thirty six RA patients were received Abatacept. The drug efficacy was evaluated with the DAS28 score after 6 months of treatment according to the EULAR response criteria. Among 36 Aba RA patients, 17 were responders and 19 were classified as no-responders. A blood sample was carried out in patients just before the first injection of treatment in PaxGene tubes. Two color experiments : patient(Cy5)/Control pool (Cy3).

ORGANISM(S): Homo sapiens  

SUBMITTER: Celine Derambure  

PROVIDER: E-GEOD-68215 | ArrayExpress | 2017-05-17

SECONDARY ACCESSION(S): GSE68215PRJNA282038

REPOSITORIES: GEO, ArrayExpress

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