Transcriptomics

Dataset Information

297

Gene expression changes in control- and shSamd14-infected R1 fetal liver


ABSTRACT: Samd14 was discovered as a novel GATA-2 target gene. Samd14 increased hematopoietic progenitor levels/activity, promoted signaling by a pathway instrumental for hematopoietic stem/progenitor cell regulation (Stem Cell Factor/c-Kit), and c-Kit rescued Samd14 loss-of-function phenotypes A control shRNA or an shRNA targeting Samd14 was retrovirally introduced to fetal liver ex vivo cultures. Progenitor cells (CD71-, Ter119-) were isolated and analyzed from these cultures

ORGANISM(S): Mus musculus  

SUBMITTER: Kyle J Hewitt   Colin N Dewey  Kyle Hewitt 

PROVIDER: E-GEOD-68602 | ArrayExpress | 2015-06-11

SECONDARY ACCESSION(S): SRP058058GSE68602PRJNA283200

REPOSITORIES: GEO, ArrayExpress, ENA

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