Transcriptomics

Dataset Information

38

Mouse lung tissue transcriptome response to a wild type infectious clone of H7N9 Influenza virus and mutant H7N9 viruses [microRNA]


ABSTRACT: The purpose is to obtain samples for mRNA, miRNA, proteomics, lipidomics, metabolomics, and histopathology analysis in mouse lung infected with WT A/Anhui/1/2013 (H7N9; 'AH1'), AH - NS1-103F/106M, and AH1 - 691 (ferret adapted virus). Groups of 22-week-old C57BL/6 mice were infected with the H7N9 Influenza WT A/Anhui/1/2013 (H7N9; 'AH1'), AH - NS1-103F/106M, and AH1 - 691 (ferret adapted virus). Infections were done at 10^4 PFU or time-matched mock infected. Time points were 1, 2, 4 and 7 d.p.i. There were 5 animals/dose/time point. Lung samples were collected for virus load, transcriptional and proteomics analysis. Weight loss and animal survival were also monitored.

ORGANISM(S): Mus musculus  

SUBMITTER: Amie J Eisfeld  Kelly Stratton   Katrina M Waters   Yoshihiro Kawaoka    

PROVIDER: E-GEOD-68946 | ArrayExpress | 2015-05-24

SECONDARY ACCESSION(S): GSE68946PRJNA284143

REPOSITORIES: GEO, ArrayExpress

altmetric image

Publications

Sorry, this publication's infomation has not been loaded in the Indexer, please go directly to PUBMED or Altmetric.

Similar Datasets

2015-05-24 | E-GEOD-68945 | ArrayExpress
2015-05-23 | E-GEOD-69026 | ArrayExpress
2015-05-23 | E-GEOD-69027 | ArrayExpress
| GSE97949 | GEO
2014-06-03 | E-GEOD-49840 | ArrayExpress
2013-07-01 | E-GEOD-48200 | ArrayExpress
2014-06-03 | E-GEOD-54048 | ArrayExpress
2018-01-29 | E-MTAB-6379 | ArrayExpress
| PRJNA430796 | ENA
| GSE114466 | GEO