Transcriptomics

Dataset Information

2

Tetraspanin 3 is Required for the Development and Propagation of Acute Myelogenous Leukemia


ABSTRACT: Msi2 is a critical regulatior of myeoid leukemia, and these data identify genes that are changed following Msi2 deletion in bcCML and de novo AML stem cells. Leukemic stem cells were extracted from wild-type and Msi2 mutant MLL-AF9 driven AML and BCR-ABL/NUP98-HOXA9 driven bcCML, in triplicate. RNA was extracted and hybridized on Affymetrix microarrays. The mouse strain was a genetic trap Msi2 mutant made by Center for Animal Resources and Development (CARD) of Kumamoto University. They call their strain B6;CB-Msi2Gt(pU-21T)2Imeg, see also http://cardb.cc.kumamoto-u.ac.jp/transgenic/strainsDetailAction.do?strainId=834

ORGANISM(S): Mus musculus  

SUBMITTER: Roman Sasik  

PROVIDER: E-GEOD-69512 | ArrayExpress | 2015-06-04

SECONDARY ACCESSION(S): GSE69512PRJNA285773

REPOSITORIES: GEO, ArrayExpress

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