Transcriptomics

Dataset Information

3

Mycobacterium tuberculosis H37Rv transcriptional response to antibacterial agents


ABSTRACT: Bacteria commonly adapt to stresses by altering gene expression. To understand the response of M. tuberculosis (MTB) to various antibacterial agents, we performed transcriptomics on MTB bacilli exposed to several test compounds as well as known drugs (capreomycin, cycloserine, ethionamide, isoniazid, kanamycin, moxifloxacin, PA-824, rifampicin, streptomycin). Bacteria were exposed for 16 hrs to various concentrations of each drug (different multiples of the compound's MIC), as noted in the title of each sample. RNA was isolated and applied to arrays provided by TIGR under the NIAID contract N01-AI-15447

ORGANISM(S): Mycobacterium tuberculosis  

SUBMITTER: Tige R Rustad   David R Sherman  Reiling P Liao  Shuyi Ma  Mark Hickey 

PROVIDER: E-GEOD-71200 | ArrayExpress | 2015-11-11

SECONDARY ACCESSION(S): GSE71200PRJNA290573

REPOSITORIES: GEO, ArrayExpress

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