Transcriptomics

Dataset Information

299

Transcriptome assay of materal mRNA degradation in Btg4-deleted oocytes


ABSTRACT: We analyzed the functions of BTG family proteins in maternal mRNA degradation in mouse oocytes. By comparing the degradation of transcripts in WT oocytes and KO oocytes, we are able to know the defects in maternal mRNA clearance in BTG4-deleted oocytes, and identified the BTG4 target genes in oocyte cyplasmic maturation. 2 WT oocyte samples at GV stage, 2 WT oocyte samples at MII stage, 2 Btg4-/- oocyte samples at GV stage and 2 Btg4-/- oocyte samples at MII stage?2 WT embryo samples at zygote stage, 2 WT embryo samples at 2-cell stage, 2 Btg4-/- embryo samples at zygote stage and 2 Btg4-/- embryo samples at 2-cell stage , and a WT GV oocyte, a WT MII oocyte, a Erk-/- GV oocyte and a Erk-/- MII oocyte are performed RNA sequencing.

ORGANISM(S): Mus musculus  

SUBMITTER: Yujiao Dang   Shu-Yan Ji  Chao Yu  yujiao dang 

PROVIDER: E-GEOD-71257 | ArrayExpress | 2016-03-16

SECONDARY ACCESSION(S): SRP061454GSE71257PRJNA290718

REPOSITORIES: GEO, ArrayExpress, ENA

Similar Datasets

2007-11-13 | E-GEOD-5668 | ArrayExpress
| GSE92317 | GEO
2011-04-25 | E-GEOD-23449 | ArrayExpress
2016-02-28 | E-GEOD-74344 | ArrayExpress
| GSE100117 | GEO
2010-07-12 | E-GEOD-12432 | ArrayExpress
| GSE95477 | GEO
2013-10-02 | E-GEOD-46640 | ArrayExpress
2016-05-26 | PXD003691 | Pride
2010-03-23 | GSE21005 | GEO