Genomics

Dataset Information

5

MeDIP-chip of adult mouse hippocampus exposed to neonatal ethanol


ABSTRACT: In this experiment, we exposed mice to ethanol injections on postnatal days 4 and 7. We then extracted whole-hippocampus on postnatal day 70. We performed MeDIP-chip using an antibody against 5mC. We also perfomed MEDME anaylsis using a chip with fully methylated DNA to act as a control. We found alterations in both modifications at many sites, including oxidative stress genes and imprinted loci. We also found many affect lipid metabolism pathways. Comparision of neonatal ethanol-injected with saline injected C57BL/6J mouse hippocampus in adulthood (day 70)

ORGANISM(S): Mus musculus  

SUBMITTER: Eric Jonathon Diehl   S M Singh  E J Diehl 

PROVIDER: E-GEOD-71313 | ArrayExpress | 2015-07-25

SECONDARY ACCESSION(S): GSE71313PRJNA290890

REPOSITORIES: GEO, ArrayExpress

Dataset's files

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Action DRS
E-GEOD-71313.idf.txt Idf
E-GEOD-71313.raw.1.zip Raw
E-GEOD-71313.raw.2.zip Raw
E-GEOD-71313.raw.3.zip Raw
E-GEOD-71313.raw.4.zip Raw
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