Transcriptomics

Dataset Information

2

Investigation of miRNA expression signatures in mTORC1 -stimulated osteoarthritis


ABSTRACT: To further explain pathology of mTORC1 -stimulated osteoarthritis, we have employed whole genome microarray expression profiling as a discovery platform to identify miRNAs which involved in development of mTORC1-stimulated osteoarthritis We generated Col2a1-specific deletion of Tsc1 mice. mTORC1 induced miRNAs expression in development of osteoarthritis was measured at eight weeks after birth. Independent experiments were performed using knee joint cartilage from Col2a1Tsc1KO and control mice.

ORGANISM(S): Mus musculus  

SUBMITTER: Hua Wang   Xiaochun Bai  hua wang 

PROVIDER: E-GEOD-71484 | ArrayExpress | 2016-07-30

SECONDARY ACCESSION(S): GSE71484PRJNA291366

REPOSITORIES: GEO, ArrayExpress

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