Transcriptomics

Dataset Information

300

Age and Nursing Affect the Neonatal Porcine Uterine Transcriptome


ABSTRACT: Age- and lactocrine-sensitive elements of the neonatal porcine uterine developmental program are undefined. Here, effects of age and nursing for 48 h from birth (postnatal day = [PND] 0) on the uterine transcriptome at PND 2 were identified using RNA sequencing. Pig uterine tissues were obtained from neonatal gilts (n = 4/group) within 1 h of birth [postnatal day (PND) 0], or 48 h after nursing ad libitum (PND 2N), or feeding a commercial milk replacer (PND 2R).

ORGANISM(S): Sus scrofa  

SUBMITTER: Carol A Bagnell   Caroll Bagnell  Frank F Bartol 

PROVIDER: E-GEOD-72388 | ArrayExpress | 2016-02-15

SECONDARY ACCESSION(S): GSE72388SRP062860PRJNA293935

REPOSITORIES: GEO, ArrayExpress, ENA

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Publications

Age and Nursing Affect the Neonatal Porcine Uterine Transcriptome.

Rahman Kathleen M KM   Camp Meredith E ME   Prasad Nripesh N   McNeel Anthony K AK   Levy Shawn E SE   Bartol Frank F FF   Bagnell Carol A CA  

Biology of reproduction 20151202 2


The lactocrine hypothesis for maternal programming of neonatal development was proposed to describe a mechanism through which milk-borne bioactive factors, delivered from mother to nursing offspring, could affect development of tissues, including the uterus. Porcine uterine development, initiated before birth, is completed postnatally. However, age- and lactocrine-sensitive elements of the neonatal porcine uterine developmental program are undefined. Here, effects of age and nursing on the uteri  ...[more]

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