Transcriptomics

Dataset Information

296

A Genome-wide mRNA Screen and Functional Analysis Reveal FOXO3 as a Candidate Gene for Chicken Growth


ABSTRACT: The objective of this study was to identify candidate genes associated with chicken growth and investigate their potential mechanisms. We used RNA-Seq to study the breast muscle transcriptome in high and low tails of Recessive White Rock (WRRh, WRRl) and Xinghua chickens (XHh, XHl). A total of 60, 23, 153 and 359 differentially expressed genes were detected in WRRh vs. WRRl, XHh vs. XHl, WRRh vs. XHh and WRRl vs. XHl, respectively. GO, KEGG pathway and gene network analyses showed that CEBPB, FBXO32, FOXO3 and MYOD1 played key roles in growth. The functions of FBXO32 and FOXO3 were validated. Examination of mRNA profiles in two-tail samples of WRR and XH strains.

ORGANISM(S): Gallus gallus  

SUBMITTER: Chen Biao   Xiaomei He  Qinghua Nie 

PROVIDER: E-GEOD-72424 | ArrayExpress | 2015-08-27

SECONDARY ACCESSION(S): GSE72424SRP062880PRJNA294010

REPOSITORIES: GEO, ArrayExpress, ENA

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