Dataset Information


Gene expression signature of HoxA9-Meis1 AML cells treated with Pyrydopyrazine

ABSTRACT: Pyrydopyrazine A2 induced in vitro the differentiation of leukemic cells (HoxA9-Meis1) into macrophages, we decided to perform a transcriptomic study in order to analyze the GM-CSF pathway regulation. We therefore compared effect with A2 to cells treated with Retinoic acid and D3 Vitamin, a combination known to induce also differentiation of leukemic cells. HoxA9-Meis1 murine AML cells were treated in vitro during 24h, with Pyrydopyrazine( A2) at 3.4μM or a combination of all-trans Retinoic Acid (RA) and 1α-hydroxy-D3 Vitamin (D3V), 10μM each. Gene expression signature was compared to untreated control. One sample was tested for each condition

ORGANISM(S): Mus musculus  

SUBMITTER: ronan quere  Ronan Quéré    

PROVIDER: E-GEOD-72635 | ArrayExpress | 2015-09-02



altmetric image


Sorry, this publication's infomation has not been loaded in the Indexer, please go directly to PUBMED or Altmetric.

Similar Datasets

2011-12-04 | E-GEOD-33509 | ArrayExpress
2018-12-30 | E-MTAB-5760 | ArrayExpress
2011-05-24 | E-GEOD-29453 | ArrayExpress
2011-11-09 | E-GEOD-33517 | ArrayExpress
2014-06-11 | E-GEOD-58359 | ArrayExpress
2014-06-11 | E-GEOD-58361 | ArrayExpress
2014-01-08 | E-GEOD-53894 | ArrayExpress
2011-12-05 | E-GEOD-33518 | ArrayExpress
2015-01-01 | E-GEOD-50645 | ArrayExpress
2014-06-11 | E-GEOD-58360 | ArrayExpress