Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Yuhua Zhang Erfan Aref-Eshghi Roger Green Proton Rahman Ming Liu Patricia E Harper Andrew Furey Guangju Zhai Guang Sun Glynn Martin
PROVIDER: E-GEOD-73626 | ArrayExpress | 2016-07-01
SECONDARY ACCESSION(S): GSE73626PRJNA297447
REPOSITORIES: GEO, ArrayExpress
BMC musculoskeletal disorders 20151009
Evidence suggests that epigenetics plays a role in osteoarthrits (OA). The aim of the study was to describe the genome wide DNA methylation changes in hip and knee OA and identify novel genes and pathways involved in OA by comparing the DNA methylome of the hip and knee osteoarthritic cartilage tissues with those of OA-free individuals.Cartilage samples were collected from hip or knee joint replacement patients either due to primary OA or hip fractures as controls. DNA was extracted from the col ...[more]