Transcriptomics

Dataset Information

2

Microarray expression profile of long noncoding RNAs in EGFR-TKI resistance of lung adenocarcinoma


ABSTRACT: Lung adenocarcinoma cells harboring epidermal growth factor receptor (EGFR) mutations are sensitive to EGFR tyrosine kinase inhibitors (TKIs). Prolonged cancer treatment will induce the development of acquired resistance to EGFR TKI. To gain insight into the molecular mechanisms of EGFR-TKIs resistance, we generate EGFR-TKI-resistant HCC827-8-1 cells to be analyzed by microarray with their parental HCC827cells. gefitinib resistant HCC827-8-1 cells with three replications; gefitinib-sensitive HCC827 cells with three replications

ORGANISM(S): Homo sapiens  

SUBMITTER: Ying Wu   Haixia Cao  Siwen Liu  Jifeng Feng  Yong Hu 

PROVIDER: E-GEOD-74575 | ArrayExpress | 2016-08-23

SECONDARY ACCESSION(S): GSE74575PRJNA300856

REPOSITORIES: GEO, ArrayExpress

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