Transcriptomics

Dataset Information

85

O-linked β-N-acetylglucosamine (O-GlcNAc) acts as a glucose sensor to epigenetically regulate the insulin gene in pancreatic beta cells


ABSTRACT: We compare global gene expression changes in the Min6 cell line in response to altered glucose flux and pharmacological manipulation of the O-GlcNAc postranslational protein modification. Min6 cells were treated for 1hr in the following conditions: Low glucose (LG), high glucose (HG) and LG+GlcNAcstatin (LG+GNS). After treatment, total RNA was extracted and used for sequencing.

ORGANISM(S): Mus musculus  

SUBMITTER: Sean P Durning  Lance Wells    

PROVIDER: E-GEOD-74980 | ArrayExpress | 2016-02-27

SECONDARY ACCESSION(S): GSE74980SRP066153PRJNA302114

REPOSITORIES: GEO, ArrayExpress, ENA

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