Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA302459PRJNA302463PRJNA302454PRJNA302462PRJNA302465PRJNA302461PRJNA302460PRJNA302457PRJNA302458PRJNA302464
ORGANISM(S): Mus Musculus
SUBMITTER: Nir Yosef Jellert Gaublomme Aviv Regev
PROVIDER: E-GEOD-75104 | ArrayExpress | 2015-11-20
SECONDARY ACCESSION(S): GSE75104SRP066313PRJNA302464
REPOSITORIES: GEO, ArrayExpress, ENA
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E-GEOD-75104.idf.txt | Idf | |||
E-GEOD-75104.processed.1.zip | Processed | |||
E-GEOD-75104.sdrf.txt | Txt |
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Cell 20151119 6
Extensive cellular heterogeneity exists within specific immune-cell subtypes classified as a single lineage, but its molecular underpinnings are rarely characterized at a genomic scale. Here, we use single-cell RNA-seq to investigate the molecular mechanisms governing heterogeneity and pathogenicity of Th17 cells isolated from the central nervous system (CNS) and lymph nodes (LN) at the peak of autoimmune encephalomyelitis (EAE) or differentiated in vitro under either pathogenic or non-pathogeni ...[more]