Transcriptomics

Dataset Information

62

Expression data from lung tissues of minipig with left lung ischemia-reperfusion


ABSTRACT: Lung ischemia-reperfusion (I/R) injury remains one of the common complications after various cardiopulmonary surgeries. I-R injury represents one potentially maladaptive response of the innate immune system which is featured by an exacerbated sterile inflammatory response triggered by tissue damage. Thus, understanding the key components and processes involved in sterile inflammation during lung I-R injury is critical to alter care and extend survival for patients with acute lung injury. We constructed a minipig surgical model of transient unilateral left pulmonary artery occlusion without bronchial involvement to create ventilated lung I-R injury. Lung tissues from minipig with sham operation (one sample), left side lung tissues (the operated side)(one sample) and right side lung tissues (the non-operated side)(one sample) from minipig with lung ischemia-reperfusion were submitted for gene expression array analysis.

ORGANISM(S): Sus scrofa  

SUBMITTER: Huimin Fan   Hao Cao  Zhongmin Liu  Zhenzhen Zhan 

PROVIDER: E-GEOD-75560 | ArrayExpress | 2015-12-07

SECONDARY ACCESSION(S): GSE75560PRJNA304600

REPOSITORIES: GEO, ArrayExpress

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